Multi‐Material Strain Mapping with Scanning Reflectance Anisotropy Microscopy

In vivo reflectance-mode confocal scanning laser microscopy in dermatology.

RCM offers tremendous potential for the advancement of medical research and clinical care. In research, it offers benefits both ex vivo and in vivo. Ex vivo, it can allow us to sample tissue and evaluate it noninvasively to determine what further testing--on the same exact tissue--may be helpful. In vivo RCM can be used to study normal or pathophysiologic processes in real-time noninvasively an...

Elemental mapping in scanning transmission electron microscopy

We discuss atomic resolution chemical mapping in scanning transmission electron microscopy (STEM) based on core-loss electron energy loss spectroscopy (EELS) and also on energy dispersive X-ray (EDX) imaging. Chemical mapping using EELS can yield counterintuitive results which, however, can be understood using first principles calculations. Experimental chemical maps based on EDX bear out the t...

Dopant Mapping of Semiconductors with Scanning Electron Microscopy

Compound semiconductor devices, as typified by laser diodes, photo diodes, and high electron mobility transistors, are used for optical communication systems, satellite communications, and cellular base stations to meet a growing demand for large-capacity and high-speed communication systems that play a key role in the infrastructure of modern society. The properties and reliability of semicond...

Noninvasive imaging of melanoma with reflectance mode confocal scanning laser microscopy in a murine model.

A reflectance-mode confocal scanning laser microscope (rCSLM) was developed for imaging early-stage melanoma in a living mouse model without the addition of exogenous contrast agents. Lesions were first located by surveying the dorsum with a polarized light camera, then imaged with the rCSLM. The images demonstrated two characteristics of melanoma in this animal model: (1) melanocytes and appar...

Strain resolution of scanning electron microscopy based Kossel microdiffraction